Last update
4/8/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 7 Reviews
8.1
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
5
Total Fat
0.5 g
1%†
Ubiquinol (as Kaneka Ubiquinol™)
100 mg
**
Top Medical Research Studies
9
We aimed to understand how ubiquinol, also known as coenzyme Q10 (CoQ-10), can impact those suffering from heart failure (HF). To do this, we conducted a thorough review of existing studies, searching databases like MEDLINE and the Cochrane Library for relevant literature.
Throughout our evaluation, we focused on key outcomes: whether CoQ-10 could reduce HF-related mortality, improve patients' exercise capacity, and affect the left ventricular ejection fraction (LVEF). Our analysis included findings from 16 different studies that provided intriguing insights.
Notably, we observed that CoQ-10 was effective in reducing HF-related mortality by an impressive 40%. Additionally, patients taking CoQ-10 reported enhanced exercise capacity, which is crucial for improving their quality of life. However, when it came to the left ventricular ejection fraction, the results were less clear; we found no significant difference, though we acknowledge that further research is needed to fully explore its potential effects in this area.
In summary, CoQ-10 shows promise in supporting heart failure patients by reducing mortality and boosting exercise capacity, but its role related to LVEF still warrants additional exploration.
Throughout our evaluation, we focused on key outcomes: whether CoQ-10 could reduce HF-related mortality, improve patients' exercise capacity, and affect the left ventricular ejection fraction (LVEF). Our analysis included findings from 16 different studies that provided intriguing insights.
Notably, we observed that CoQ-10 was effective in reducing HF-related mortality by an impressive 40%. Additionally, patients taking CoQ-10 reported enhanced exercise capacity, which is crucial for improving their quality of life. However, when it came to the left ventricular ejection fraction, the results were less clear; we found no significant difference, though we acknowledge that further research is needed to fully explore its potential effects in this area.
In summary, CoQ-10 shows promise in supporting heart failure patients by reducing mortality and boosting exercise capacity, but its role related to LVEF still warrants additional exploration.
Read More
Most Useful Reviews
7.5
Improved energy levels
4 people found this helpful
A Superior Ubiquinol Type of Q10! My dad takes this supplement to assist with his cardiovascular disease. He feels a boost in energy and less fatigue when taking it. Most Q10 supplements are an inferior type - ubiquinone - which explains the price difference. Ubiquinol is better absorbed according to clinical research, which is why I chose this product. Iherb offers a competitive price and my dad takes only one softgel per day. They’re fairly big but he doesn’t have trouble swallowing them. He had a mini stroke six months ago and this is one of the products he's been using for recovery, which is going so well he plans to continue with this superior ubiquinol type of Q10 for his well-being. A great supplement from a trusted brand!
Read More
9
Great quality supplement
The quality is good. Since it is a fat-soluble nutrient, it is said to be better absorbed when taken after a fatty meal. It’s excellent for preventing cardiovascular disease and possesses antioxidant effects, so I take it every day.
Read More
7.5
Increased energy levels
I started taking Life Extension Super Ubiquinol CoQ10 and within a few weeks noticed a positive change in how I felt. The softgels are easy to swallow and contain 100 mg of ubiquinol, which is better absorbed by the body. I chose this product to support my energy and cardiovascular health, and it has exceeded my expectations. I feel more energetic and less tired after workouts, with improved focus and mood. The additional mitochondrial support ingredients enhance its effectiveness. Overall, this product has become a vital part of my diet and I would recommend it to anyone wishing to maintain their health and active lifestyle.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
- All Researches
9
We aimed to understand how ubiquinol, also known as coenzyme Q10 (CoQ-10), can impact those suffering from heart failure (HF). To do this, we conducted a thorough review of existing studies, searching databases like MEDLINE and the Cochrane Library for relevant literature.
Throughout our evaluation, we focused on key outcomes: whether CoQ-10 could reduce HF-related mortality, improve patients' exercise capacity, and affect the left ventricular ejection fraction (LVEF). Our analysis included findings from 16 different studies that provided intriguing insights.
Notably, we observed that CoQ-10 was effective in reducing HF-related mortality by an impressive 40%. Additionally, patients taking CoQ-10 reported enhanced exercise capacity, which is crucial for improving their quality of life. However, when it came to the left ventricular ejection fraction, the results were less clear; we found no significant difference, though we acknowledge that further research is needed to fully explore its potential effects in this area.
In summary, CoQ-10 shows promise in supporting heart failure patients by reducing mortality and boosting exercise capacity, but its role related to LVEF still warrants additional exploration.
Throughout our evaluation, we focused on key outcomes: whether CoQ-10 could reduce HF-related mortality, improve patients' exercise capacity, and affect the left ventricular ejection fraction (LVEF). Our analysis included findings from 16 different studies that provided intriguing insights.
Notably, we observed that CoQ-10 was effective in reducing HF-related mortality by an impressive 40%. Additionally, patients taking CoQ-10 reported enhanced exercise capacity, which is crucial for improving their quality of life. However, when it came to the left ventricular ejection fraction, the results were less clear; we found no significant difference, though we acknowledge that further research is needed to fully explore its potential effects in this area.
In summary, CoQ-10 shows promise in supporting heart failure patients by reducing mortality and boosting exercise capacity, but its role related to LVEF still warrants additional exploration.
Read More
User Reviews
USERS' SCORE
Good
Based on 7 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Improved energy levels
4 people found this helpful
A Superior Ubiquinol Type of Q10! My dad takes this supplement to assist with his cardiovascular disease. He feels a boost in energy and less fatigue when taking it. Most Q10 supplements are an inferior type - ubiquinone - which explains the price difference. Ubiquinol is better absorbed according to clinical research, which is why I chose this product. Iherb offers a competitive price and my dad takes only one softgel per day. They’re fairly big but he doesn’t have trouble swallowing them. He had a mini stroke six months ago and this is one of the products he's been using for recovery, which is going so well he plans to continue with this superior ubiquinol type of Q10 for his well-being. A great supplement from a trusted brand!
Read More
9
Great quality supplement
The quality is good. Since it is a fat-soluble nutrient, it is said to be better absorbed when taken after a fatty meal. It’s excellent for preventing cardiovascular disease and possesses antioxidant effects, so I take it every day.
Read More
7.5
Increased energy levels
I started taking Life Extension Super Ubiquinol CoQ10 and within a few weeks noticed a positive change in how I felt. The softgels are easy to swallow and contain 100 mg of ubiquinol, which is better absorbed by the body. I chose this product to support my energy and cardiovascular health, and it has exceeded my expectations. I feel more energetic and less tired after workouts, with improved focus and mood. The additional mitochondrial support ingredients enhance its effectiveness. Overall, this product has become a vital part of my diet and I would recommend it to anyone wishing to maintain their health and active lifestyle.
Read More
7.5
Essential for heart function
Coenzyme Q10 is essential for ATP production, which cells use to generate energy, especially in high-energy organs like the heart and liver. Ubiquinol, the non-oxidised form of CoQ10, offers greater bioavailability and helps reduce oxidative stress at the cellular level, benefiting cardiovascular and overall health. Your heart needs CoQ10, but its levels naturally decrease over time. This formula contains 100 mg of bioavailable coenzyme Q10 ubiquinol.
Read More
7.5
Preventative measure
I take 2 of these per day alongside diet and exercise to protect against cardiovascular disease, which runs in my family.
Read More
Frequently Asked Questions
7.5
Increased energy levels
I started taking Life Extension Super Ubiquinol CoQ10 and within a few weeks noticed a positive change in how I felt. The softgels are easy to swallow and contain 100 mg of ubiquinol, which is better absorbed by the body. I chose this product to support my energy and cardiovascular health, and it has exceeded my expectations. I feel more energetic and less tired after workouts, with improved focus and mood. The additional mitochondrial support ingredients enhance its effectiveness. Overall, this product has become a vital part of my diet and I would recommend it to anyone wishing to maintain their health and active lifestyle.
9
Great quality supplement
The quality is good. Since it is a fat-soluble nutrient, it is said to be better absorbed when taken after a fatty meal. It’s excellent for preventing cardiovascular disease and possesses antioxidant effects, so I take it every day.
7.5
Improved energy levels
4 people found this helpful
A Superior Ubiquinol Type of Q10! My dad takes this supplement to assist with his cardiovascular disease. He feels a boost in energy and less fatigue when taking it. Most Q10 supplements are an inferior type - ubiquinone - which explains the price difference. Ubiquinol is better absorbed according to clinical research, which is why I chose this product. Iherb offers a competitive price and my dad takes only one softgel per day. They’re fairly big but he doesn’t have trouble swallowing them. He had a mini stroke six months ago and this is one of the products he's been using for recovery, which is going so well he plans to continue with this superior ubiquinol type of Q10 for his well-being. A great supplement from a trusted brand!
7.5
Essential for heart function
Coenzyme Q10 is essential for ATP production, which cells use to generate energy, especially in high-energy organs like the heart and liver. Ubiquinol, the non-oxidised form of CoQ10, offers greater bioavailability and helps reduce oxidative stress at the cellular level, benefiting cardiovascular and overall health. Your heart needs CoQ10, but its levels naturally decrease over time. This formula contains 100 mg of bioavailable coenzyme Q10 ubiquinol.
7.5
Preventative measure
I take 2 of these per day alongside diet and exercise to protect against cardiovascular disease, which runs in my family.
9
We aimed to understand how ubiquinol, also known as coenzyme Q10 (CoQ-10), can impact those suffering from heart failure (HF). To do this, we conducted a thorough review of existing studies, searching databases like MEDLINE and the Cochrane Library for relevant literature.
Throughout our evaluation, we focused on key outcomes: whether CoQ-10 could reduce HF-related mortality, improve patients' exercise capacity, and affect the left ventricular ejection fraction (LVEF). Our analysis included findings from 16 different studies that provided intriguing insights.
Notably, we observed that CoQ-10 was effective in reducing HF-related mortality by an impressive 40%. Additionally, patients taking CoQ-10 reported enhanced exercise capacity, which is crucial for improving their quality of life. However, when it came to the left ventricular ejection fraction, the results were less clear; we found no significant difference, though we acknowledge that further research is needed to fully explore its potential effects in this area.
In summary, CoQ-10 shows promise in supporting heart failure patients by reducing mortality and boosting exercise capacity, but its role related to LVEF still warrants additional exploration.
Throughout our evaluation, we focused on key outcomes: whether CoQ-10 could reduce HF-related mortality, improve patients' exercise capacity, and affect the left ventricular ejection fraction (LVEF). Our analysis included findings from 16 different studies that provided intriguing insights.
Notably, we observed that CoQ-10 was effective in reducing HF-related mortality by an impressive 40%. Additionally, patients taking CoQ-10 reported enhanced exercise capacity, which is crucial for improving their quality of life. However, when it came to the left ventricular ejection fraction, the results were less clear; we found no significant difference, though we acknowledge that further research is needed to fully explore its potential effects in this area.
In summary, CoQ-10 shows promise in supporting heart failure patients by reducing mortality and boosting exercise capacity, but its role related to LVEF still warrants additional exploration.
References
- Qazi SU, Bin Naeem MA, Umar M, Zahid MJ, Kan Changez MI, et al. Evaluating the efficacy of ubiquinol in heart failure patients: a systematic review and meta-analysis. Future Cardiol. 2024;20:221. 10.1080/14796678.2024.2352308
Data last updated:
